Desmond is the man

Desmond is special because he’s the only person who is only one person in both worlds. That is: there’s an Island Jack and a Sideways Jack: two Jacks. There’s an Island Kate and a Sideways Kate: two Kates. Etc, etc. But there’s only one Desmond. Whether in the Sideways world or the Island world, it’s the same Desmond. Widmore’s jolt fused the two. Now Desmond knows both worlds. In fact, he knows everything; more than any character on the show now; more than we know. He’s the most powerful man on Lost. Fear is weakness and he’s absolutely without fear. Knowledge is power and he has more knowledge than anyone else, including the Man in Black.

Wondering why Desmond ran over Locke? So am I. But the most significant thing about that scene was not what Desmond did, but the fact that he knew exactly what he was doing when he did it. He knows. He freaking knows it all. Desmond is the man.